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Effects of extracellular pH on agonism and antagonism at a recombinant P2X(2) receptor

1. Under voltage-clamp conditions, the activity of agonists and antagonists at a recombinant P2X(2) receptor expressed in Xenopus oocytes was examined at different levels of extracellular pH (pH(e)). 2. In normal Ringer (Mg(2+) ions absent), the amplitude of submaximal inward currents to ATP was inc...

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Bibliographic Details
Main Authors: King, B F, Wildman, S S, Ziganshina, L E, Pintor, J, Burnstock, G
Format: Artigo
Language:Inglês
Published: 1997
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564844/
https://ncbi.nlm.nih.gov/pubmed/9257926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701286
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