Effects of the non-peptide B(2) antagonist FR173657 on kinin-induced smooth muscle contraction and relaxation, vasoconstriction and prostaglandin release

1. The non-peptide bradykinin (BK) antagonist (E)-3-(6-acetamido-3-pyridyl)-N-[N-[2,4-dichloro-3-[(2- methyl-8-quinolinyl)oxymethyl]phenyl]-N-methylaminocarbonylmethyl]acrylamide (FR173657) was tested in intestinal, uterine, tracheal and vascular in vitro preparations. The investigation aimed at det...

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Autores principales: Griesbacher, Thomas, Sametz, Wolfgang, Legat, Franz J, Diethart, Sabine, Hammer, Susanne, Juan, Heinz
Formato: Artigo
Lenguaje:Inglês
Publicado: 1997
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Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564713/
https://ncbi.nlm.nih.gov/pubmed/9179388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701159
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