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Effects of FR173657, a non-peptide B(2) antagonist, on kinin-induced hypotension, visceral and peripheral oedema formation and bronchoconstriction

1. Kinins are believed to play a key role in many inflammatory conditions. Therefore, bradykinin antagonists are being developed for potential therapeutic applications. In the present investigation we describe the pharmacology, in vivo, of (E)-3-(6- acetamido- 3-pyridyl)- N-[N- [2,4- dichloro- 3-[(2...

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Detalhes bibliográficos
Main Authors: Griesbacher, Thomas, Legat, Franz J
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564532/
https://ncbi.nlm.nih.gov/pubmed/9138701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0700966
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