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Effect of copper on nitric oxide synthase and guanylyl cyclase activity in the rat isolated aorta
1. The potential role of copper (Cu(2+)) in modulating the activity of nitric oxide synthase (NOS) and guanylyl cyclase (GC) was investigated by use of diethyldithiocarbamic acid (DEDCA), a high affinity Cu(2+) chelator. 2. DEDCA 100 μM inhibited sodium nitroprusside (SNP; 0.005–10 μM)-evoked relaxa...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1564688/ https://ncbi.nlm.nih.gov/pubmed/9154347 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701144 |
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