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Dissociation of lipopolysaccharide-mediated induction of nitric oxide synthase and inhibition of DNA synthesis in RAW 264.7 macrophages and rat aortic smooth muscle cells
1. The active component of endotoxin, lipopolysaccharide (LPS), inhibited basal DNA synthesis in both RAW 264.7 macrophages (IC(50) 0.05±0.03 μg ml(−1)) and rat aortic smooth muscle cells (RASMC) (IC(50) 9.7±0.4 μg ml(−1)). 2. In both cell types, serum differentially affected LPS-stimulated inhibiti...
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| Asıl Yazarlar: | , , , , |
|---|---|
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
1997
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1564627/ https://ncbi.nlm.nih.gov/pubmed/9113363 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701070 |
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