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The effects of recombinant rat μ-opioid receptor activation in CHO cells on phospholipase C, [Ca(2+)](i) and adenylyl cyclase
1. The rat μ-opioid receptor has recently been cloned, yet its second messenger coupling remains unclear. The endogenous μ-opioid receptor in SH-SY5Y cells couples to phospholipase C (PLC), increases [Ca(2+)](i) and inhibits adenylyl cyclase (AC). We have examined the effects of μ-opioid agonists on...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
1997
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1564574/ https://ncbi.nlm.nih.gov/pubmed/9134231 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701012 |
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