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The inhibitory effect of the antipsychotic drug haloperidol on HERG potassium channels expressed in Xenopus oocytes

1. The antipsychotic drug haloperidol can induce a marked QT prolongation and polymorphic ventricular arrhythmias. In this study, we expressed several cloned cardiac K(+) channels, including the human ether-a-go-go related gene (HERG) channels, in Xenopus oocytes and tested them for their haloperido...

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Detalhes bibliográficos
Main Authors: Suessbrich, H, Schönherr, R, Heinemann, S H, Attali, B, Lang, F, Busch, A E
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564549/
https://ncbi.nlm.nih.gov/pubmed/9138706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0700989
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