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Inhibition of a spliceosome turnover pathway suppresses splicing defects
Defects in assembly are suggested to signal the dissociation of faulty splicing complexes. A yeast genetic screen was performed to identify components of the putative discard pathway. Weak mutant alleles of SPP382 (also called NTR1) were found to suppress defects in two proteins required for spliceo...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1564266/ https://ncbi.nlm.nih.gov/pubmed/16945917 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0603188103 |
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