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NikR–operator complex structure and the mechanism of repressor activation by metal ions

Metal ion homeostasis is critical to the survival of all cells. Regulation of nickel concentrations in Escherichia coli is mediated by the NikR repressor via nickel-induced transcriptional repression of the nickel ABC-type transporter, NikABCDE. Here, we report two crystal structures of nickel-activ...

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Autors principals: Schreiter, Eric R., Wang, Sheila C., Zamble, Deborah B., Drennan, Catherine L.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564233/
https://ncbi.nlm.nih.gov/pubmed/16945905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0606247103
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