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Structural Basis of Low-Affinity Nickel Binding to the Nickel-Responsive Transcription Factor NikR from Escherichia coli

[Image: see text] Escherichia coli NikR regulates cellular nickel uptake by binding to the nik operon in the presence of nickel and blocking transcription of genes encoding the nickel uptake transporter. NikR has two binding affinities for the nik operon: a nanomolar dissociation constant with stoic...

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Autors principals: Phillips, Christine M., Schreiter, Eric R., Stultz, Collin M., Drennan, Catherine L.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2010
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2934763/
https://ncbi.nlm.nih.gov/pubmed/20704276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100923j
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