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Cyclobutane pyrimidine dimers are predominant DNA lesions in whole human skin exposed to UVA radiation

Solar UV radiation is the most important environmental factor involved in the pathogenesis of skin cancers. The well known genotoxic properties of UVB radiation (290–320 nm) mostly involve bipyrimidine DNA photoproducts. In contrast, the contribution of more-abundant UVA radiation (320–400 nm) that...

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Bibliografiske detaljer
Main Authors: Mouret, Stéphane, Baudouin, Caroline, Charveron, Marie, Favier, Alain, Cadet, Jean, Douki, Thierry
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564232/
https://ncbi.nlm.nih.gov/pubmed/16954188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604213103
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