Crystal Structure of Nonstructural Protein 10 from the Severe Acute Respiratory Syndrome Coronavirus Reveals a Novel Fold with Two Zinc-Binding Motifs

The severe acute respiratory syndrome coronavirus (SARS-CoV) possesses a large 29.7-kb positive-stranded RNA genome. The first open reading frame encodes replicase polyproteins 1a and 1ab, which are cleaved to generate 16 “nonstructural” proteins, nsp1 to nsp16, involved in viral replication and/or...

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Detalhes bibliográficos
Main Authors: Joseph, Jeremiah S., Saikatendu, Kumar Singh, Subramanian, Vanitha, Neuman, Benjamin W., Brooun, Alexei, Griffith, Mark, Moy, Kin, Yadav, Maneesh K., Velasquez, Jeffrey, Buchmeier, Michael J., Stevens, Raymond C., Kuhn, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Structure and Assembly
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1563791/
https://ncbi.nlm.nih.gov/pubmed/16873246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00467-06
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