Fourier Transform Infrared Spectroscopy Provides a Fingerprint for the Tetramer and for the Aggregates of Transthyretin

Transthyretin (TTR) is an amyloidogenic protein whose aggregation is responsible for several familial amyloid diseases. Here, we use FTIR to describe the secondary structural changes that take place when wt TTR undergoes heat- or high-pressure-induced denaturation, as well as fibril formation. Upon...

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Detalhes bibliográficos
Main Authors: Cordeiro, Yraima, Kraineva, Julia, Suarez, Marisa Carvalho, Tempesta, Anna Gabriella, Kelly, Jeffery W., Silva, Jerson L., Winter, Roland, Foguel, Debora
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2006
Assuntos:
Proteins
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1563765/
https://ncbi.nlm.nih.gov/pubmed/16698785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.085928
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