Generation of a Reporter Cell Line for Detection of Infectious Varicella-Zoster Virus and Its Application to Antiviral Studies

To simplify the titration of infectious varicella-zoster virus (VZV), we generated a reporter cell line that produced luciferase in a dose-dependent manner upon infection with cell-free VZV. A few VZV-infected cells were detectable by coculturing with the cell line. We demonstrated the usefulness of...

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Main Authors: Wang, Guan-Qing, Suzutani, Tatsuo, Yamamoto, Yumiko, Fukui, Yoshiko, Nozawa, Naoki, Schmid, D. Scott, Kurane, Ichiro, Inoue, Naoki
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2006
Assuntos:
Antiviral Agents
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1563536/
https://ncbi.nlm.nih.gov/pubmed/16940113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00342-06
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