تحميل...
Metabolic Activation of Pradefovir by CYP3A4 and Its Potential as an Inhibitor or Inducer
Metabolic activation of pradefovir to 9-(2-phosphonylmethoxyethyl)adenine (PMEA) was evaluated by using cDNA-expressed CYP isozymes in portal vein-cannulated rats following oral administration and in human liver microsomes. The enzyme induction potential of pradefovir was evaluated in rats following...
محفوظ في:
| المؤلفون الرئيسيون: | , , , , |
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| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
American Society for Microbiology
2006
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1563525/ https://ncbi.nlm.nih.gov/pubmed/16940083 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01566-05 |
| الوسوم: |
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