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Tetracyclines Specifically Target the Apicoplast of the Malaria Parasite Plasmodium falciparum
Tetracyclines are effective but slow-acting antimalarial drugs whose mechanism of action remains uncertain. To characterize the antimalarial mechanism of tetracyclines, we evaluated their stage-specific activities, impacts on parasite transcription, and effects on two predicted organelle targets, th...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1563505/ https://ncbi.nlm.nih.gov/pubmed/16940111 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00394-06 |
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