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Follicular Dendritic Cell Dedifferentiation by Treatment with an Inhibitor of the Lymphotoxin Pathway Dramatically Reduces Scrapie Susceptibility

Transmissible spongiform encephalopathies (TSEs) may be acquired peripherally, in which case infectivity usually accumulates in lymphoid tissues before dissemination to the nervous system. Studies of mouse scrapie models have shown that mature follicular dendritic cells (FDCs), expressing the host p...

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Bibliografische gegevens
Hoofdauteurs: Mabbott, Neil A., Young, Janice, McConnell, Irene, Bruce, Moira E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2003
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC156207/
https://ncbi.nlm.nih.gov/pubmed/12768004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.12.6845-6854.2003
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