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Generation of Transduction-Competent Retroviral Vectors by Infection with a Single Hybrid Vaccinia Virus

Recombinant vaccinia viruses that express defective retroviral vectors upon a single infection event in normal host cells were constructed. The gag-pol and envelope genes and a retroviral vector unit were inserted as vaccinia virus promoter-controlled transcription units at three separate loci. The...

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Detalhes bibliográficos
Main Authors: Konetschny, Christian, Holzer, Georg W., Urban, Carsten, Hämmerle, Thomas, Mayrhofer, Josef, Falkner, Falko G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC156191/
https://ncbi.nlm.nih.gov/pubmed/12768020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.12.7017-7025.2003
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