Cytolysis by CCR5-Using Human Immunodeficiency Virus Type 1 Envelope Glycoproteins Is Dependent on Membrane Fusion and Can Be Inhibited by High Levels of CD4 Expression

T-tropic (X4) and dualtropic (R5X4) human immunodeficiency virus type 1 (HIV-1) envelope glycoproteins kill primary and immortalized CD4(+) CXCR4(+) T cells by mechanisms involving membrane fusion. However, because much of HIV-1 infection in vivo is mediated by M-tropic (R5) viruses whose envelope g...

ver descrição completa

Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	LaBonte, Jason A., Madani, Navid, Sodroski, Joseph
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2003
Assuntos:	Virus-Cell Interactions
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC156190/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12767984/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.12.6645-6659.2003
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!