Polymorphisms in Chlamydia trachomatis tryptophan synthase genes differentiate between genital and ocular isolates

We previously reported that laboratory reference strains of Chlamydia trachomatis differing in infection organotropism correlated with inactivating mutations in the pathogen’s tryptophan synthase (trpBA) genes. Here, we have applied functional genomics to extend this work and find that the paradigm...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Caldwell, Harlan D., Wood, Heidi, Crane, Debbie, Bailey, Robin, Jones, Robert B., Mabey, David, Maclean, Ian, Mohammed, Zeena, Peeling, Rosanna, Roshick, Christine, Schachter, Julius, Solomon, Anthony W., Stamm, Walter E., Suchland, Robert J., Taylor, Lacey, West, Sheila K., Quinn, Tom C., Belland, Robert J., McClarty, Grant
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 2003
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC156111/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12782678/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI17993
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