Polymorphisms in Chlamydia trachomatis tryptophan synthase genes differentiate between genital and ocular isolates

We previously reported that laboratory reference strains of Chlamydia trachomatis differing in infection organotropism correlated with inactivating mutations in the pathogen’s tryptophan synthase (trpBA) genes. Here, we have applied functional genomics to extend this work and find that the paradigm...

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Autori principali: Caldwell, Harlan D., Wood, Heidi, Crane, Debbie, Bailey, Robin, Jones, Robert B., Mabey, David, Maclean, Ian, Mohammed, Zeena, Peeling, Rosanna, Roshick, Christine, Schachter, Julius, Solomon, Anthony W., Stamm, Walter E., Suchland, Robert J., Taylor, Lacey, West, Sheila K., Quinn, Tom C., Belland, Robert J., McClarty, Grant
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2003
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC156111/
https://ncbi.nlm.nih.gov/pubmed/12782678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200317993
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