Polymorphisms in Chlamydia trachomatis tryptophan synthase genes differentiate between genital and ocular isolates

We previously reported that laboratory reference strains of Chlamydia trachomatis differing in infection organotropism correlated with inactivating mutations in the pathogen’s tryptophan synthase (trpBA) genes. Here, we have applied functional genomics to extend this work and find that the paradigm...

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Main Authors: Caldwell, Harlan D., Wood, Heidi, Crane, Debbie, Bailey, Robin, Jones, Robert B., Mabey, David, Maclean, Ian, Mohammed, Zeena, Peeling, Rosanna, Roshick, Christine, Schachter, Julius, Solomon, Anthony W., Stamm, Walter E., Suchland, Robert J., Taylor, Lacey, West, Sheila K., Quinn, Tom C., Belland, Robert J., McClarty, Grant
格式: Artigo
語言:Inglês
出版: American Society for Clinical Investigation 2003
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC156111/
https://ncbi.nlm.nih.gov/pubmed/12782678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200317993
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