Polymorphisms in Chlamydia trachomatis tryptophan synthase genes differentiate between genital and ocular isolates

We previously reported that laboratory reference strains of Chlamydia trachomatis differing in infection organotropism correlated with inactivating mutations in the pathogen’s tryptophan synthase (trpBA) genes. Here, we have applied functional genomics to extend this work and find that the paradigm...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Caldwell, Harlan D., Wood, Heidi, Crane, Debbie, Bailey, Robin, Jones, Robert B., Mabey, David, Maclean, Ian, Mohammed, Zeena, Peeling, Rosanna, Roshick, Christine, Schachter, Julius, Solomon, Anthony W., Stamm, Walter E., Suchland, Robert J., Taylor, Lacey, West, Sheila K., Quinn, Tom C., Belland, Robert J., McClarty, Grant
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 2003
Schlagworte:	Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC156111/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12782678/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI17993
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