CTG repeat instability and size variation timing in DNA repair-deficient mice

Type 1 myotonic dystrophy is caused by the expansion of an unstable CTG repeat in the DMPK gene. We have investigated the molecular mechanisms underlying the CTG repeat instability by crossing transgenic mice carrying >300 unstable CTG repeats in their human chromatin environment with mice knockout...

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Dades bibliogràfiques

Publicat a:	EMBO J
Autors principals:	Savouret, Cédric, Brisson, Edith, Essers, Jeroen, Kanaar, Roland, Pastink, Albert, te Riele, Hein, Junien, Claudine, Gourdon, Geneviève
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Publishing Group 2003
Matèries:	Articles
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC156074/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12727892/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg202
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