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CTG repeat instability and size variation timing in DNA repair-deficient mice
Type 1 myotonic dystrophy is caused by the expansion of an unstable CTG repeat in the DMPK gene. We have investigated the molecular mechanisms underlying the CTG repeat instability by crossing transgenic mice carrying >300 unstable CTG repeats in their human chromatin environment with mice knocko...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC156074/ https://ncbi.nlm.nih.gov/pubmed/12727892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg202 |
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