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CTG repeat instability and size variation timing in DNA repair-deficient mice

Type 1 myotonic dystrophy is caused by the expansion of an unstable CTG repeat in the DMPK gene. We have investigated the molecular mechanisms underlying the CTG repeat instability by crossing transgenic mice carrying >300 unstable CTG repeats in their human chromatin environment with mice knockout...

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Publicado no:EMBO J
Principais autores: Savouret, Cédric, Brisson, Edith, Essers, Jeroen, Kanaar, Roland, Pastink, Albert, te Riele, Hein, Junien, Claudine, Gourdon, Geneviève
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2003
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Articles
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC156074/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12727892/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg202
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