CTG repeat instability and size variation timing in DNA repair-deficient mice

Type 1 myotonic dystrophy is caused by the expansion of an unstable CTG repeat in the DMPK gene. We have investigated the molecular mechanisms underlying the CTG repeat instability by crossing transgenic mice carrying >300 unstable CTG repeats in their human chromatin environment with mice knockout...

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Bibliografiske detaljer

Udgivet i:	EMBO J
Principais autores:	Savouret, Cédric, Brisson, Edith, Essers, Jeroen, Kanaar, Roland, Pastink, Albert, te Riele, Hein, Junien, Claudine, Gourdon, Geneviève
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Publishing Group 2003
Fag:	Articles
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC156074/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12727892/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg202
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