Llwytho...

CTG repeat instability and size variation timing in DNA repair-deficient mice

Type 1 myotonic dystrophy is caused by the expansion of an unstable CTG repeat in the DMPK gene. We have investigated the molecular mechanisms underlying the CTG repeat instability by crossing transgenic mice carrying >300 unstable CTG repeats in their human chromatin environment with mice knocko...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Savouret, Cédric, Brisson, Edith, Essers, Jeroen, Kanaar, Roland, Pastink, Albert, te Riele, Hein, Junien, Claudine, Gourdon, Geneviève
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2003
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC156074/
https://ncbi.nlm.nih.gov/pubmed/12727892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg202
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