Targeted ablation of ILK from the murine heart results in dilated cardiomyopathy and spontaneous heart failure

A requirement for integrin-mediated adhesion in cardiac physiology is revealed through targeted deletion of inte-grin-associated genes in the murine heart. Here we show that targeted ablation of the integrin-linked kinase (ILK) expression results in spontaneous cardiomyopathy and heart failure by 6...

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Bibliografiske detaljer
Main Authors: White, Donald E., Coutu, Pierre, Shi, Yan-Fen, Tardif, Jean-Claude, Nattel, Stanley, Arnaud, RenéSt., Dedhar, Shoukat, Muller, William J.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2006
Fag:
Research Communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1560410/
https://ncbi.nlm.nih.gov/pubmed/16951252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1458906
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