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Stable T cell-dendritic cell interactions precede the development of both tolerance and immunity in vivo

The maturation status of dendritic cells (DCs) determines whether they prime or tolerize T cells. We targeted ovalbumin peptide exclusively to DCs in situ using an antibody against DEC-205 and studied DC interaction with naïve CD4(+) T cells under tolerizing or priming conditions. Two-photon microsc...

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Detalles Bibliográficos
Main Authors: Shakhar, Guy, Lindquist, Randall L., Skokos, Dimitris, Dudziak, Diana, Huang, Julie H., Nussenzweig, Michel C., Dustin, Michael L.
Formato: Artigo
Idioma:Inglês
Publicado: 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1560107/
https://ncbi.nlm.nih.gov/pubmed/15924144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni1210
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