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Stable T cell-dendritic cell interactions precede the development of both tolerance and immunity in vivo
The maturation status of dendritic cells (DCs) determines whether they prime or tolerize T cells. We targeted ovalbumin peptide exclusively to DCs in situ using an antibody against DEC-205 and studied DC interaction with naïve CD4(+) T cells under tolerizing or priming conditions. Two-photon microsc...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1560107/ https://ncbi.nlm.nih.gov/pubmed/15924144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni1210 |
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