Transcarboxylase 12S crystal structure: hexamer assembly and substrate binding to a multienzyme core

Transcarboxylase from Propionibacterium shermanii is a 1.2 MDa multienzyme complex that couples two carboxylation reactions, transferring CO(2)(–) from methylmalonyl-CoA to pyruvate, yielding propionyl-CoA and oxaloacetate. The 1.9 Å resolution crystal structure of the central 12S hexameric core, wh...

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Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Hall, Pamela R., Wang, Yan-Fei, Rivera-Hainaj, Rosa E., Zheng, Xiaojing, Pustai-Carey, Marianne, Carey, Paul R., Yee, Vivien C.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 2003
Assuntos:	Articles
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC156002/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12743028/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg244
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