Transcarboxylase 12S crystal structure: hexamer assembly and substrate binding to a multienzyme core
Transcarboxylase from Propionibacterium shermanii is a 1.2 MDa multienzyme complex that couples two carboxylation reactions, transferring CO(2)(–) from methylmalonyl-CoA to pyruvate, yielding propionyl-CoA and oxaloacetate. The 1.9 Å resolution crystal structure of the central 12S hexameric core, wh...
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| 發表在: | EMBO J |
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| Principais autores: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group
2003
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC156002/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12743028/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg244 |
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