Proteolytic processing is necessary to separate and ensure proper cell growth and cytokinesis functions of HCF-1

HCF-1 is a highly conserved and abundant chromatin-associated host cell factor required for transcriptional activation of herpes simplex virus immediate-early genes by the virion protein VP16. HCF-1 exists as a heterodimeric complex of associated N- (HCF-1(N)) and C- (HCF-1(C)) terminal subunits tha...

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Veröffentlicht in:	EMBO J
Hauptverfasser:	Julien, Eric, Herr, Winship
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Publishing Group 2003
Schlagworte:	Articles
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC156000/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12743030/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg242
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