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Proteolytic processing is necessary to separate and ensure proper cell growth and cytokinesis functions of HCF-1

HCF-1 is a highly conserved and abundant chromatin-associated host cell factor required for transcriptional activation of herpes simplex virus immediate-early genes by the virion protein VP16. HCF-1 exists as a heterodimeric complex of associated N- (HCF-1(N)) and C- (HCF-1(C)) terminal subunits tha...

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Detalhes bibliográficos
Main Authors: Julien, Eric, Herr, Winship
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC156000/
https://ncbi.nlm.nih.gov/pubmed/12743030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg242
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