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Opposing functions of ZEB proteins in the regulation of the TGFβ/BMP signaling pathway

Binding of TGFβ/BMP factors to their receptors leads to translocation of Smad proteins to the nucleus where they activate transcription of target genes. The two-handed zinc finger proteins encoded by Zfhx1a and Zfhx1b, ZEB-1/δEF1 and ZEB-2/SIP1, respectively, regulate gene expression and differentia...

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Bibliografske podrobnosti
Glavni avtor: Postigo, Antonio A.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2003
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC155983/
https://ncbi.nlm.nih.gov/pubmed/12743038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg225
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