Human cytomegalovirus-encoded chemokine receptor US28 promotes tumorigenesis

Human cytomegalovirus (HCMV) is a widely spread herpesvirus, suggested to play a role in tumor progression. US28, a chemokine receptor encoded by HCMV, binds a broad spectrum of chemokines and constitutively activates various pathways linked to proliferation. Our studies reveal that expression of US...

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Main Authors: Maussang, David, Verzijl, Dennis, van Walsum, Marijke, Leurs, Rob, Holl, Jens, Pleskoff, Olivier, Michel, Detlef, van Dongen, Guus A. M. S., Smit, Martine J.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2006
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1559754/
https://ncbi.nlm.nih.gov/pubmed/16924106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604433103
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