Targeted deletion of Gpbar1 protects mice from cholesterol gallstone formation

The Gpbar1 [G-protein-coupled BA (bile acid) receptor 1] is a recently identified cell-surface receptor that can bind and is activated by BAs, but its physiological role is unclear. Using targeted deletion of the Gpbar1 gene in mice, we show that the gene plays a critical role in the maintenance of...

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Detalhes bibliográficos
Main Authors: Vassileva, Galya, Golovko, Andrei, Markowitz, Lisa, Abbondanzo, Susan J., Zeng, Ming, Yang, Shijun, Hoos, Lizbeth, Tetzloff, Glen, Levitan, Diane, Murgolo, Nicholas J., Keane, Kevin, Davis, Harry R., Hedrick, Joseph, Gustafson, Eric L.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2006
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1559456/
https://ncbi.nlm.nih.gov/pubmed/16724960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060537
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