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Targeted deletion of Gpbar1 protects mice from cholesterol gallstone formation
The Gpbar1 [G-protein-coupled BA (bile acid) receptor 1] is a recently identified cell-surface receptor that can bind and is activated by BAs, but its physiological role is unclear. Using targeted deletion of the Gpbar1 gene in mice, we show that the gene plays a critical role in the maintenance of...
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| Główni autorzy: | , , , , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Portland Press Ltd.
2006
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1559456/ https://ncbi.nlm.nih.gov/pubmed/16724960 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060537 |
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