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Mechanisms of RecQ helicases in pathways of DNA metabolism and maintenance of genomic stability

Helicases are molecular motor proteins that couple the hydrolysis of NTP to nucleic acid unwinding. The growing number of DNA helicases implicated in human disease suggests that their vital specialized roles in cellular pathways are important for the maintenance of genome stability. In particular, m...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Sharma, Sudha, Doherty, Kevin M., Brosh, Robert M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Portland Press Ltd. 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1559444/
https://ncbi.nlm.nih.gov/pubmed/16925525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060450
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