In vivo HIV-1 infection of CD45RA(+)CD4(+) T cells is established primarily by syncytium-inducing variants and correlates with the rate of CD4(+) T cell decline

Switch from non-syncytium-inducing (NSI) to syncytium-inducing (SI) HIV type 1 (HIV-1) is associated with accelerated CD4(+) T cell depletion, which might partially be explained by higher virulence of SI variants compared with NSI variants. Because NSI and SI variants use different coreceptors for e...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Blaak, Hetty, van't Wout, Angélique B., Brouwer, Margreet, Hooibrink, Berend, Hovenkamp, Egbert, Schuitemaker, Hanneke
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2000
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15592/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10655520/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.3.1269
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