Human Immunodeficiency Virus Type 1 Pathogenesis in SCID-hu Mice Correlates with Syncytium-Inducing Phenotype and Viral Replication

Human immunodeficiency virus type 1 (HIV-1) patient isolates and molecular clones were used to analyze the determinants responsible for human CD4(+) thymocyte depletion in SCID-hu mice. Non-syncytium-inducing, R5 or R3R5 HIV-1 isolates from asymptomatic infected people showed little or no human CD4(...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Camerini, David, Su, Hua-Poo, Gamez-Torre, Graciela, Johnson, Michael L., Zack, Jerome A., Chen, Irvin S. Y.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 2000
विषय:
Pathogenesis and Immunity
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC111820/
https://ncbi.nlm.nih.gov/pubmed/10708436
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