Mutual genetic antagonism involving GLI3 and dHAND prepatterns the vertebrate limb bud mesenchyme prior to SHH signaling

The bHLH transcription factor dHAND is required for establishment of SHH signaling by the limb bud organizer in posterior mesenchyme, a step crucial to development of vertebrate paired appendages. We show that the transcriptional repressor GLI3 restricts dHAND expression to posterior mesenchyme prio...

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Autors principals: te Welscher, Pascal, Fernandez-Teran, Marian, Ros, Marian A., Zeller, Rolf
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2002
Matèries:
Research Communication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC155343/
https://ncbi.nlm.nih.gov/pubmed/11850405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.219202
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