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The zinc-finger proto-oncogene Gfi-1b is essential for development of the erythroid and megakaryocytic lineages

Gfi-1 and Gfi-1b are novel proto-oncogenes identified by retroviral insertional mutagenesis. By gene targeting, we establish that Gfi-1b is required for the development of two related blood lineages, erythroid and megakaryocytic, in mice. Gfi-1b(−/−) embryonic stem cells fail to contribute to red ce...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Genes Dev
Päätekijät: Saleque, Shireen, Cameron, Scott, Orkin, Stuart H.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cold Spring Harbor Laboratory Press 2002
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC155332/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11825872/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.959102
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