The zinc-finger proto-oncogene Gfi-1b is essential for development of the erythroid and megakaryocytic lineages
Gfi-1 and Gfi-1b are novel proto-oncogenes identified by retroviral insertional mutagenesis. By gene targeting, we establish that Gfi-1b is required for the development of two related blood lineages, erythroid and megakaryocytic, in mice. Gfi-1b(−/−) embryonic stem cells fail to contribute to red ce...
Guardat en:
| Publicat a: | Genes Dev |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
2002
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC155332/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11825872/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.959102 |
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