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The zinc-finger proto-oncogene Gfi-1b is essential for development of the erythroid and megakaryocytic lineages
Gfi-1 and Gfi-1b are novel proto-oncogenes identified by retroviral insertional mutagenesis. By gene targeting, we establish that Gfi-1b is required for the development of two related blood lineages, erythroid and megakaryocytic, in mice. Gfi-1b(−/−) embryonic stem cells fail to contribute to red ce...
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| Glavni autori: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Cold Spring Harbor Laboratory Press
2002
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC155332/ https://ncbi.nlm.nih.gov/pubmed/11825872 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.959102 |
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