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WISP-1 attenuates p53-mediated apoptosis in response to DNA damage through activation of the Akt kinase

WISP-1 (Wnt-1-induced secreted protein) was identified as an oncogene regulated by the Wnt-1–β-catenin pathway. WISP-1 belongs to the CCN family of growth factors, which are cysteine-rich, heparin-binding, secreted proteins associated with the extracellular matrix, and can interact with cellular int...

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Detalhes bibliográficos
Main Authors: Su, Fei, Overholtzer, Michael, Besser, Daniel, Levine, Arnold J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC155313/
https://ncbi.nlm.nih.gov/pubmed/11782444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.942902
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