p27(Kip1) Inhibition of GRB2-SOS Formation Can Regulate Ras Activation

p27(Kip1) (p27) is often inappropriately downregulated in aggressive human cancers. Although p27 can inhibit cyclin-dependent kinases (CDKs), low p27 does not always correlate with increased CDK activity. Furthermore, cells derived from p27(−/−) mice respond to antimitogens, maintain restriction poi...

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Podrobná bibliografie

Vydáno v:	Mol Cell Biol
Hlavní autoři:	Moeller, Stephanie J., Head, Elizabeth D., Sheaff, Robert J.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Taylor & Francis 2003
Témata:	Cell Growth and Development
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC155227/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12748278/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.11.3735-3752.2003
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