Regulation of BRCA1 Transcription by Specific Single-Stranded DNA Binding Factors

Since the majority of high-grade breast cancers express reduced levels of BRCA1 mRNA, we investigated the factors regulating BRCA1 transcription. Factors with specific affinity for the previously identified positive regulatory region (PRR) in the BRCA1 promoter were purified from whole-cell extracts...

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Detalhes bibliográficos
Main Authors: Thakur, Sanjay, Nakamura, Tatsuya, Calin, George, Russo, Andrea, Tamburrino, Joseph F., Shimizu, Masayoshi, Baldassarre, Gustavo, Battista, Sabrina, Fusco, Alfredo, Wassell, Richard P., Dubois, Garret, Alder, Hansjuerg, Croce, Carlo M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Transcriptional Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC155225/
https://ncbi.nlm.nih.gov/pubmed/12748281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.11.3774-3787.2003
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