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Regulation of BRCA1 Transcription by Specific Single-Stranded DNA Binding Factors

Since the majority of high-grade breast cancers express reduced levels of BRCA1 mRNA, we investigated the factors regulating BRCA1 transcription. Factors with specific affinity for the previously identified positive regulatory region (PRR) in the BRCA1 promoter were purified from whole-cell extracts...

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Main Authors: Thakur, Sanjay, Nakamura, Tatsuya, Calin, George, Russo, Andrea, Tamburrino, Joseph F., Shimizu, Masayoshi, Baldassarre, Gustavo, Battista, Sabrina, Fusco, Alfredo, Wassell, Richard P., Dubois, Garret, Alder, Hansjuerg, Croce, Carlo M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC155225/
https://ncbi.nlm.nih.gov/pubmed/12748281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.11.3774-3787.2003
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