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Regulation of BRCA1 Transcription by Specific Single-Stranded DNA Binding Factors
Since the majority of high-grade breast cancers express reduced levels of BRCA1 mRNA, we investigated the factors regulating BRCA1 transcription. Factors with specific affinity for the previously identified positive regulatory region (PRR) in the BRCA1 promoter were purified from whole-cell extracts...
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| Main Authors: | , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology
2003
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC155225/ https://ncbi.nlm.nih.gov/pubmed/12748281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.11.3774-3787.2003 |
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