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Regulation of BRCA1 expression and its relationship to sporadic breast cancer

Germ-line mutations in the BRCA1 tumour suppressor gene contribute to familial breast tumour formation, but there is no evidence for direct mutation of the BRCA1 gene in the sporadic form of the disease. In contrast, decreased expression of the BRCA1 gene has been shown to be common in sporadic tumo...

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Autori principali: Mueller, Christopher R, Roskelley, Calvin D
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC154136/
https://ncbi.nlm.nih.gov/pubmed/12559046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr557
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