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Regulation of BRCA1 expression and its relationship to sporadic breast cancer

Germ-line mutations in the BRCA1 tumour suppressor gene contribute to familial breast tumour formation, but there is no evidence for direct mutation of the BRCA1 gene in the sporadic form of the disease. In contrast, decreased expression of the BRCA1 gene has been shown to be common in sporadic tumo...

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Autors principals: Mueller, Christopher R, Roskelley, Calvin D
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2003
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC154136/
https://ncbi.nlm.nih.gov/pubmed/12559046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr557
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