Inactivation of Dual-Specificity Phosphatases Is Involved in the Regulation of Extracellular Signal-Regulated Kinases by Heat Shock and Hsp72

Extracellular signal-regulated kinase 1 (ERK1) and ERK2 (ERK1/2) dramatically enhance survival of cells exposed to heat shock. Using Cos-7 cells and primary human fibroblasts (IMR90 cells), we demonstrated that heat shock activates ERKs via two distinct mechanisms: stimulation of the ERK-activating...

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Bibliographic Details

Published in:	Mol Cell Biol
Main Authors:	Yaglom, Julia, O'Callaghan-Sunol, Cornelia, Gabai, Vladimir, Sherman, Michael Y.
Format:	Artigo
Language:	Inglês
Published:	Taylor & Francis 2003
Subjects:	Cell Growth and Development
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC155207/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12748284/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.11.3813-3824.2003
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