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Structure and Function of the Voltage Sensor of Sodium Channels Probed by a β-Scorpion Toxin
Voltage sensing by voltage-gated sodium channels determines the electrical excitability of cells, but the molecular mechanism is unknown. β-Scorpion toxins bind specifically to neurotoxin receptor site 4 and induce a negative shift in the voltage dependence of activation through a voltage sensor-tra...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2006
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1551974/ https://ncbi.nlm.nih.gov/pubmed/16679310 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M603814200 |
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